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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Extensive Stage Small Cell Lung Cancer (ES-SCLC)

Maintenance Lurbinectedin in Combination With Serplulimab for Patients With ES-SCLC NCT06497530Phase 21 site๐Ÿ“ Guangzhou Guangzhou Institute of Respiratory Disease ยท Tests: Serplulimab, Lurbinectedin, Carboplatin, Etoposide Liposomal Irinotecan and Apatinib in ES-SCLC NCT06749691Phase 21 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: Liposomal Irinotecan and Apatinib Second-line Immunotherapy for ES-SCLC NCT06853678NA1 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: Adebrelimab, Selinexor, Nab-paclitaxel A Prospective, Single-Arm, Single-Center Phase II Study Evaluating the Efficacy and Safety of Chidamide Combined With PD-L1 Inhibitor, Carboplatin, and Etoposide as First-Line Treatment in Patients With Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) NCT07373964Phase 21 site๐Ÿ“ Shenyang China Medical University, China ยท Tests: Chidamide Tablets๏ผ› PD-L1 Inhibitor (as per chosen drug's prescribing information)๏ผ›Carboplatin๏ผ› Etoposide Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation NCT06110572Phase 1, Phase 21 site๐Ÿ“ Nashville Vanderbilt-Ingram Cancer Center ยท Tests: Carboplatin, Atezolizumab, Etoposide, Total Body Irradiation, Hypofractionated Radiation Therapy A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC NCT07459634Phase 25 sites๐Ÿ“ Los Angeles๐Ÿ“ Jacksonville๐Ÿ“ Atlanta Jazz Pharmaceuticals ยท Tests: Lurbinectedin, Durvalumab A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03) NCT06362252Phase 1, Phase 258 sites๐Ÿ“ Birmingham๐Ÿ“ Phoenix๐Ÿ“ Los Angeles Daiichi Sankyo ยท Tests: Ifinatamab deruxtecan, Atezolizumab, Carboplatin Durvalumab With Consolidative Radiochemotherapy and Ablative Stereotactic Radiotherapy in Oligometastatic ES-SCLC NCT06223711Phase 25 sites๐Ÿ“ Augsburg๐Ÿ“ Erlangen๐Ÿ“ Regensburg Universitรคt des Saarlandes ยท Tests: Thoracic Radiochemotherapy, durvalumab, Stereotactic radiotherapy of further tumor locations, Chemotherapy Post-line Treatment With Teniposide for c-Myc-driven Extensive-stage Small Cell Lung Cancer NCT06758700Phase 21 site๐Ÿ“ Shanghai Shanghai Pulmonary Hospital, Shanghai, China ยท Tests: Teniposide administration A Phase I Study to Evaluate the Safety and Preliminary Efficacy of [225Ac]Ac-DOTATATE Injection Combined With Tislelizumab in the Maintenance Treatment Period for Patients of Extensive-stage Small Cell Lung Cancer (ES-SCLC) With Somatostatin Receptors (SSTR)+ as First-line Treatment NCT07413042Phase 11 site๐Ÿ“ Beijing Peking University Cancer Hospital & Institute ยท Tests: [225Ac]Ac-DOTATATE A Study of [225Ac]Ac-AKY-2519 in Patients With B7-H3 Expressing Solid Tumors NCT07887971Phase 11 site๐Ÿ“ Miami Aktis Oncology, Inc. ยท Tests: [225Ac]Ac-AKY-2519 (therapeutic), [64Cu]Cu-AKY-2519 (imaging) Small Extracellular Vesicle miRNAs as Predictive Biomarkers for Immunochemotherapy Efficacy in Extensive-stage Small Cell Lung Cancer NCT07070011n/a1 site๐Ÿ“ Shanghai Shanghai Chest Hospital of Shanghai Jiao Tong University ยท Tests: EC/EP + ICIs A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer NCT07155174Phase 270 sites๐Ÿ“ New Haven๐Ÿ“ Gainesville๐Ÿ“ Ocala AbbVie ยท Tests: ABBV-706, Atezolizumab, Etoposide, Carboplatin, Carboplatin Pembrolizumab and Olaparib Treatment of Extensive Small Cell Lung Cancer (ES-SCLC) NCT05623319Phase 212 sites๐Ÿ“ Meldola๐Ÿ“ Monza๐Ÿ“ Pesaro Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRโ€ฆ ยท Tests: Pembrolizumab/Olaparib Tislelizumab Combined With Chemotherapy Followed by Thoracic Consolidation Radiotherapy in the First-line Treatment of Extensive Stage Small Cell Lung Cancer NCT07425795Phase 21 site๐Ÿ“ Chongqing Chongqing University Cancer Hospital ยท Tests: Tislelizumab Combined With Chemotherapy First Line Pembrolizumab, Plinabulin Plus Etoposide and Platinum (EP) for ES-SCLC NCT05745350Phase 21 site๐Ÿ“ Wuhan Xiaorong Dong ยท Tests: Pembrolizumab, Plinabulin plus Etoposide and Platinum Tislelizumab Combined With Chemotherapy and Thoracic Radiotherapy in ES-SCLC NCT06536868Phase 26 sites๐Ÿ“ Jincheng๐Ÿ“ Jinzhong๐Ÿ“ Taiyuan Second Hospital of Shanxi Medical University ยท Tests: Tislelizumab, Etoposide, Carboplatin or Cisplatin, Thoracic radiotherapy Metronomic Oral Paclitaxel Plus PD-1/ PD-L1 Inhibitor Maintenance in Advanced Lung Cancer (PULSE Study) NCT07744698Phase 41 site๐Ÿ“ Hefei Anhui Provincial Cancer Hospital ยท Tests: Paclitaxel Oral Solution, PD-1/PD-L1 inhibitor (eg. Tislelizumab) A Study to Assess the Safety and Tolerability of BMS-986525 Alone and in Combination Therapy in Participants With Relapsed/Refractory Small Cell Lung Cancer NCT07325136Phase 1, Phase 213 sites๐Ÿ“ Detroit๐Ÿ“ Buffalo๐Ÿ“ Durham Bristol-Myers Squibb ยท Tests: BMS-986525, Pumitamig A Study to Evaluate DJI136, a DLL3-targeted CAR-T Therapy NCT07564401Phase 1, Phase 27 sites๐Ÿ“ Lexington๐Ÿ“ Houston๐Ÿ“ Seattle Novartis Pharmaceuticals ยท Tests: DJI136 Adebrelimab Combine With Etoposide Capsules in ES-SCLC Maintenance Therapy NCT07141264Phase 21 site๐Ÿ“ Xi'an Tang-Du Hospital ยท Tests: Adebrelimab combined with Etoposide Capsules Study of Sacituzumab Govitecan With Atezolizumab/Durvalumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer NCT07339059Phase 21 site๐Ÿ“ Detroit Bindu R Potugari ยท Tests: Sacituzumab govitecan, Atezolizumab, Durvalumab Golidocitinib With PD-1 Inhibitors as Maintenance Treatment for Previously Untreated ES-SCLC NCT07110103Phase 22 sites๐Ÿ“ Beijing๐Ÿ“ Chongqing Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: golidocitinib with PD-1 inhibitors Iadademstat + SBRT With Atezo in ES-SCLC NCT07113691Phase 11 site๐Ÿ“ New Haven Yale University ยท Tests: Iadademstat, Atezolizumab, SBRT Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study NCT06769126Phase 2148 sites๐Ÿ“ Loma Linda๐Ÿ“ Rancho Mirage๐Ÿ“ Sacramento SWOG Cancer Research Network ยท Tests: Biospecimen Collection, Ceralasertib, Computed Tomography, Durvalumab, Etoposide Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-SCLC Patients NCT05703971Phase 1, Phase 217 sites๐Ÿ“ Lone Tree๐Ÿ“ St Louis๐Ÿ“ Canton Genprex, Inc. ยท Tests: quaratusugene ozeplasmid, atezolizumab Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer NCT06801834Phase 3219 sites๐Ÿ“ Anchorage๐Ÿ“ Hot Springs๐Ÿ“ Anaheim Gilead Sciences ยท Tests: Sacituzumab Govitecan (SG), Topotecan, Amrubicin (Japan only), Lurbinectedin (regions/countries where approved and avaiโ€ฆ A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311) NCT07037758Phase 119 sites๐Ÿ“ Gilbert๐Ÿ“ Los Angeles๐Ÿ“ Tampa Amgen ยท Tests: Tarlatamab, AB248 Phase II Study of Ivonescimab and Cadonilimab in Combination with Chemotherapy in Patients with ES-SCLC NCT06769971Phase 21 site๐Ÿ“ Chengdu Sichuan University ยท Tests: Ivonescimab, Cadonilimab, Etoposide, Carboplatin A Study of Ivonescimab in First-Line ES-SCLC NCT07245446Phase 23 sites๐Ÿ“ Beijing๐Ÿ“ Xi'an๐Ÿ“ Shanghai Akeso ยท Tests: Ivonescimab, Cadonilimab, AK117, Etoposide, Carboplatin (AUC 5)
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