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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for HFrEF - Heart Failure With Reduced Ejection Fraction

S086 Tablets for Chronic Heart Failure With Reduced Ejection Fraction NCT05553886Phase 31 site๐Ÿ“ Shenzhen Shenzhen People's Hospital ยท Tests: To evaluate whether the efficacy of the study drug is noninferior to that of the positive control drug Vericiguat and Reverse Remodeling Indices in Heart Failure NCT07405944Phase 44 sites๐Ÿ“ Izola๐Ÿ“ Ljubljana๐Ÿ“ Ljubljana University Medical Centre Ljubljana ยท Tests: Vericiguat, Guideline Directed Medical Therapy for Heart Failure (GDMT) Heart Failure in Patients With Diabetes: Cells, Crosstalk and Consequences NCT06774014n/a1 site๐Ÿ“ Leeds University of Leeds The Effect of Obesity and Weight Loss in Heart Failure With Reduced Ejection Fraction. NCT05942287NA2 sites๐Ÿ“ Jersey๐Ÿ“ Oxford University of Oxford ยท Tests: Diet intervention Surgical Versus Percutaneous Revascularization in Patients With Reduced Left Ventricular Function (STICH 3.0-NL) NCT07269366NA1 site๐Ÿ“ Groningen University Medical Center Groningen ยท Tests: CABG, PCI Guideline Implementation and Quality of Care Evaluation in Patients With Heart Failure and Reduced Ejection Fraction (HFrEF) NCT07702760n/a1 site๐Ÿ“ Rotterdam Jasper Brugts MD PhD Single and Twice-daily Dosing of Ramipril on Renal Function in Chronic Kidney Disease Patients With Reduced Ejection Fraction Heart Failure NCT07259512Phase 41 site๐Ÿ“ Kartasura Evi Liliek Wulandari ยท Tests: Ramipril Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes NCT06108076EARLY Phase 11 site๐Ÿ“ San Antonio The University of Texas Health Science Center at San Antonio ยท Tests: Ketone Monoester (KE) Exercise Capacity Improvement by Conduction System Pacing in heArt Failure patieNts Without Compelling CRT inDication NCT06278844NA1 site๐Ÿ“ Edegem University Hospital, Antwerp ยท Tests: Conduction system pacing, Right ventricular apical pacing Alleviant ALLAY-HFrEF Study NCT06812533NA70 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Sacramento Alleviant Medical, Inc. ยท Tests: Alleviant ALV1 System, Sham-Control Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure NCT06526988NA5 sites๐Ÿ“ Walnut Creek๐Ÿ“ Aurora๐Ÿ“ New Haven University of Colorado, Denver ยท Tests: EPIC-HF Patient-facing Tool, PROMPT-HF Clinician-facing Alert Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart Failure NCT06423599Phase 2, Phase 31 site๐Ÿ“ Copenhagen Jens D Hove, MD,PHD ยท Tests: Semaglutide Injectable Product, Calorie-restricted diet Olive Oil Supplementation for Heart Failure With Reduced Ejection Fraction NCT07644806NA1 site๐Ÿ“ Norfolk Old Dominion University ยท Tests: Extra-virgin olive oil Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced Cardiomyopathy NCT06128980Phase 2, Phase 31 site๐Ÿ“ Copenhagen Herlev and Gentofte Hospital ยท Tests: GDMT AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor NCT06699056n/a8 sites๐Ÿ“ Orange๐Ÿ“ Pasadena๐Ÿ“ Detroit Peerbridge Health, Inc ยท Tests: 15-minutes of sitting during COR ECG Acquistion Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol in Heart Failure With Reduced Ejection Fraction Patients With Low vs. High Polygenic Score NCT07490067Phase 41 site๐Ÿ“ Ann Arbor University of Michigan ยท Tests: Metoprolol Succinate, Beta-Blocker Polygenic Score, Illumina Infinium Global Diversity Array with Enhanced Pharmacogenoโ€ฆ Dietary Intervention and Physical Activity in Patients With Heart Failure and Reduced Ejection Fraction NCT07595809NA1 site๐Ÿ“ Zabrze Medical University of Silesia ยท Tests: Resistance Exercise, Dietary Intervention Improving CRT Outcome With Non-Invasive Cardiac Mapping NCT05564793NA11 sites๐Ÿ“ Amsterdam๐Ÿ“ Groningen๐Ÿ“ Leiden EP Solutions SA ยท Tests: Pre-implantation planning, Post-implantation assessment A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction NCT07465653Phase 16 sites๐Ÿ“ Bradenton๐Ÿ“ Inverness๐Ÿ“ Jacksonville Novartis Pharmaceuticals ยท Tests: HJB647 low dose, HJB647 high dose, Placebo Yoga Based Cardiac Rehabilitation in Heart Failure Failure NCT07817589NA16 sites๐Ÿ“ Dharwad๐Ÿ“ Mysore๐Ÿ“ Shillong Centre for Chronic Disease Control, India ยท Tests: Yoga-CaRe HF, Health Education Demographic, Clinical, Biological, Treatment Characteristics and Cardiovascular Events of Patients With Heart Failure in Vietnam: a Multicenter Prospective Observational Study NCT06516562n/a1 site๐Ÿ“ Ho Chi Minh City University Medical Center Ho Chi Minh City (UMC) ยท Tests: Optimal treatment Resistance Exercise With Blood Flow Restriction by Vascular Occlusion on Myocardial Function in Heart Failure With Reduced Ejection Fraction NCT07118410NA1 site๐Ÿ“ Nรฎmes Centre Hospitalier Universitaire de Nฤซmes ยท Tests: Application of a vascular restriction device during resistance training Eccentric Muscle Training in Cardiac Rehabilitation NCT07636343NA1 site๐Ÿ“ Edegem University Hospital, Antwerp ยท Tests: eccentric bike training, eccentric overload training, aerobic treadmill training, aerobic bike training, traditional dyโ€ฆ CardiAMP Heart Failure II Trial for Patients With Ischemic Heart Failure With Reduced Ejection Fraction NCT06258447NA5 sites๐Ÿ“ Clearwater๐Ÿ“ Atlanta๐Ÿ“ Detroit BioCardia, Inc. ยท Tests: Autologous bone marrow mononuclear cells processed / delivered using the CardiAMP cell therapy system Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure NCT06552637NA5 sites๐Ÿ“ Indianapolis๐Ÿ“ Tulsa๐Ÿ“ Philadelphia VisCardia Inc. ยท Tests: Synchronized Diaphragmatic Stimulation Pharmacological Optimization in Prevention in Heart Failure: A Sex-gap? NCT07295522Phase 412 sites๐Ÿ“ San Donato Milanese๐Ÿ“ Ancona๐Ÿ“ Cecina IRCCS Policlinico S. Donato ยท Tests: Guideline-Directed Medical Therapy (GDMT) Respiratory Sinus Arrhythmia Pacing Post-CABG Surgery in Patients With HFrEF NCT06384963NA3 sites๐Ÿ“ Adelaide๐Ÿ“ Melbourne๐Ÿ“ Hamilton Ceryx Medical Australia ยท Tests: Atrial pacing with respiratory sinus arrhythmia (RSA) variability, Monotonic right atrial overdrive pacing An Observational Study to Learn More About the Use of Vericiguat in Korean People With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) in Real-world Setting NCT06148935n/a1 site๐Ÿ“ Multiple Locations Bayer ยท Tests: Vericiguat (Verquvo, BAY1021189) Comparison of Three-dimensional and Two-dimensional Left Ventricle Strain With Speckle-tracking Echocardiography in Heart Failure With Reduced and Mildly Reduced Ejection Fraction NCT07741305n/a5 sites๐Ÿ“ Bari๐Ÿ“ Milan๐Ÿ“ Pavia Istituti Clinici Scientifici Maugeri SpA Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction NCT06736574Phase 3209 sites๐Ÿ“ Alexander City๐Ÿ“ Birmingham๐Ÿ“ Tucson Cytokinetics ยท Tests: Omecamtiv Mecarbil (OM), Placebo
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