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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Heart Failure With Reduced Ejection Fraction

Study to Collect High-Resolution ECG Data and Patient Insights on Heart Failure Care NCT06809686n/a2 sites๐Ÿ“ London๐Ÿ“ London Richmond Research Institute S086 Tablets for Chronic Heart Failure With Reduced Ejection Fraction NCT05553886Phase 31 site๐Ÿ“ Shenzhen Shenzhen People's Hospital ยท Tests: To evaluate whether the efficacy of the study drug is noninferior to that of the positive control drug Vericiguat and Reverse Remodeling Indices in Heart Failure NCT07405944Phase 44 sites๐Ÿ“ Izola๐Ÿ“ Ljubljana๐Ÿ“ Ljubljana University Medical Centre Ljubljana ยท Tests: Vericiguat, Guideline Directed Medical Therapy for Heart Failure (GDMT) Heart Failure in Patients With Diabetes: Cells, Crosstalk and Consequences NCT06774014n/a1 site๐Ÿ“ Leeds University of Leeds The Effect of Obesity and Weight Loss in Heart Failure With Reduced Ejection Fraction. NCT05942287NA2 sites๐Ÿ“ Jersey๐Ÿ“ Oxford University of Oxford ยท Tests: Diet intervention Surgical Versus Percutaneous Revascularization in Patients With Reduced Left Ventricular Function (STICH 3.0-NL) NCT07269366NA1 site๐Ÿ“ Groningen University Medical Center Groningen ยท Tests: CABG, PCI Guideline Implementation and Quality of Care Evaluation in Patients With Heart Failure and Reduced Ejection Fraction (HFrEF) NCT07702760n/a1 site๐Ÿ“ Rotterdam Jasper Brugts MD PhD Single and Twice-daily Dosing of Ramipril on Renal Function in Chronic Kidney Disease Patients With Reduced Ejection Fraction Heart Failure NCT07259512Phase 41 site๐Ÿ“ Kartasura Evi Liliek Wulandari ยท Tests: Ramipril Assessment of CCM in HF With Higher Ejection Fraction NCT05064709NA67 sites๐Ÿ“ Birmingham๐Ÿ“ Mesa๐Ÿ“ Mesa Impulse Dynamics ยท Tests: Cardiac Contractility Modulation Therapy via OPTIMIZERโ„ข Smart Mini System, OPTIMIZERโ„ข Smart Mini System Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes NCT06108076EARLY Phase 11 site๐Ÿ“ San Antonio The University of Texas Health Science Center at San Antonio ยท Tests: Ketone Monoester (KE) Exercise Capacity Improvement by Conduction System Pacing in heArt Failure patieNts Without Compelling CRT inDication NCT06278844NA1 site๐Ÿ“ Edegem University Hospital, Antwerp ยท Tests: Conduction system pacing, Right ventricular apical pacing Alleviant ALLAY-HFrEF Study NCT06812533NA70 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Sacramento Alleviant Medical, Inc. ยท Tests: Alleviant ALV1 System, Sham-Control Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure NCT06526988NA5 sites๐Ÿ“ Walnut Creek๐Ÿ“ Aurora๐Ÿ“ New Haven University of Colorado, Denver ยท Tests: EPIC-HF Patient-facing Tool, PROMPT-HF Clinician-facing Alert UPBEAT: Using Polygenic Scores to Guide BB Therapy in HF With Mildly Reduced EF NCT07054489NA1 site๐Ÿ“ Detroit David Lanfear ยท Tests: Beta blocker Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart Failure NCT06423599Phase 2, Phase 31 site๐Ÿ“ Copenhagen Jens D Hove, MD,PHD ยท Tests: Semaglutide Injectable Product, Calorie-restricted diet Olive Oil Supplementation for Heart Failure With Reduced Ejection Fraction NCT07644806NA1 site๐Ÿ“ Norfolk Old Dominion University ยท Tests: Extra-virgin olive oil Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced Cardiomyopathy NCT06128980Phase 2, Phase 31 site๐Ÿ“ Copenhagen Herlev and Gentofte Hospital ยท Tests: GDMT AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor NCT06699056n/a8 sites๐Ÿ“ Orange๐Ÿ“ Pasadena๐Ÿ“ Detroit Peerbridge Health, Inc ยท Tests: 15-minutes of sitting during COR ECG Acquistion A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists NCT06033950Phase 3176 sites๐Ÿ“ Fairhope๐Ÿ“ Phoenix๐Ÿ“ Yuma Colorado Prevention Center ยท Tests: Finerenone, Placebo Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol in Heart Failure With Reduced Ejection Fraction Patients With Low vs. High Polygenic Score NCT07490067Phase 41 site๐Ÿ“ Ann Arbor University of Michigan ยท Tests: Metoprolol Succinate, Beta-Blocker Polygenic Score, Illumina Infinium Global Diversity Array with Enhanced Pharmacogenoโ€ฆ Dietary Intervention and Physical Activity in Patients With Heart Failure and Reduced Ejection Fraction NCT07595809NA1 site๐Ÿ“ Zabrze Medical University of Silesia ยท Tests: Resistance Exercise, Dietary Intervention Improving CRT Outcome With Non-Invasive Cardiac Mapping NCT05564793NA11 sites๐Ÿ“ Amsterdam๐Ÿ“ Groningen๐Ÿ“ Leiden EP Solutions SA ยท Tests: Pre-implantation planning, Post-implantation assessment A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction NCT07465653Phase 16 sites๐Ÿ“ Bradenton๐Ÿ“ Inverness๐Ÿ“ Jacksonville Novartis Pharmaceuticals ยท Tests: HJB647 low dose, HJB647 high dose, Placebo Yoga Based Cardiac Rehabilitation in Heart Failure Failure NCT07817589NA16 sites๐Ÿ“ Dharwad๐Ÿ“ Mysore๐Ÿ“ Shillong Centre for Chronic Disease Control, India ยท Tests: Yoga-CaRe HF, Health Education Demographic, Clinical, Biological, Treatment Characteristics and Cardiovascular Events of Patients With Heart Failure in Vietnam: a Multicenter Prospective Observational Study NCT06516562n/a1 site๐Ÿ“ Ho Chi Minh City University Medical Center Ho Chi Minh City (UMC) ยท Tests: Optimal treatment A Research Study Comparing CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Reduced/Mildly Reduced Ejection Fraction and Left Ventricular Hypertrophy NCT06979375Phase 292 sites๐Ÿ“ Concord๐Ÿ“ Brisbane๐Ÿ“ Adelaide Novo Nordisk A/S ยท Tests: CDR132L, Placebo Resistance Exercise With Blood Flow Restriction by Vascular Occlusion on Myocardial Function in Heart Failure With Reduced Ejection Fraction NCT07118410NA1 site๐Ÿ“ Nรฎmes Centre Hospitalier Universitaire de Nฤซmes ยท Tests: Application of a vascular restriction device during resistance training Eccentric Muscle Training in Cardiac Rehabilitation NCT07636343NA1 site๐Ÿ“ Edegem University Hospital, Antwerp ยท Tests: eccentric bike training, eccentric overload training, aerobic treadmill training, aerobic bike training, traditional dyโ€ฆ CardiAMP Heart Failure II Trial for Patients With Ischemic Heart Failure With Reduced Ejection Fraction NCT06258447NA5 sites๐Ÿ“ Clearwater๐Ÿ“ Atlanta๐Ÿ“ Detroit BioCardia, Inc. ยท Tests: Autologous bone marrow mononuclear cells processed / delivered using the CardiAMP cell therapy system Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure NCT06552637NA5 sites๐Ÿ“ Indianapolis๐Ÿ“ Tulsa๐Ÿ“ Philadelphia VisCardia Inc. ยท Tests: Synchronized Diaphragmatic Stimulation
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