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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Heart Failure and Reduced Ejection Fraction

Study to Collect High-Resolution ECG Data and Patient Insights on Heart Failure Care NCT06809686n/a2 sites📍 London📍 London Richmond Research Institute S086 Tablets for Chronic Heart Failure With Reduced Ejection Fraction NCT05553886Phase 31 site📍 Shenzhen Shenzhen People's Hospital · Tests: To evaluate whether the efficacy of the study drug is noninferior to that of the positive control drug Vericiguat and Reverse Remodeling Indices in Heart Failure NCT07405944Phase 44 sites📍 Izola📍 Ljubljana📍 Ljubljana University Medical Centre Ljubljana · Tests: Vericiguat, Guideline Directed Medical Therapy for Heart Failure (GDMT) Heart Failure in Patients With Diabetes: Cells, Crosstalk and Consequences NCT06774014n/a1 site📍 Leeds University of Leeds The Effect of Obesity and Weight Loss in Heart Failure With Reduced Ejection Fraction. NCT05942287NA2 sites📍 Jersey📍 Oxford University of Oxford · Tests: Diet intervention Guideline Implementation and Quality of Care Evaluation in Patients With Heart Failure and Reduced Ejection Fraction (HFrEF) NCT07702760n/a1 site📍 Rotterdam Jasper Brugts MD PhD Single and Twice-daily Dosing of Ramipril on Renal Function in Chronic Kidney Disease Patients With Reduced Ejection Fraction Heart Failure NCT07259512Phase 41 site📍 Kartasura Evi Liliek Wulandari · Tests: Ramipril Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes NCT06108076EARLY Phase 11 site📍 San Antonio The University of Texas Health Science Center at San Antonio · Tests: Ketone Monoester (KE) Infusing Needed Iron to Target Insufficiency in Adults Treated for Evidence of Heart Failure NCT07467668NA1 site📍 Pleasanton Kaiser Permanente · Tests: Notification Group, No Notification Group Exercise Capacity Improvement by Conduction System Pacing in heArt Failure patieNts Without Compelling CRT inDication NCT06278844NA1 site📍 Edegem University Hospital, Antwerp · Tests: Conduction system pacing, Right ventricular apical pacing Alleviant ALLAY-HFrEF Study NCT06812533NA70 sites📍 Los Angeles📍 Los Angeles📍 Sacramento Alleviant Medical, Inc. · Tests: Alleviant ALV1 System, Sham-Control Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure NCT06526988NA5 sites📍 Walnut Creek📍 Aurora📍 New Haven University of Colorado, Denver · Tests: EPIC-HF Patient-facing Tool, PROMPT-HF Clinician-facing Alert Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart Failure NCT06423599Phase 2, Phase 31 site📍 Copenhagen Jens D Hove, MD,PHD · Tests: Semaglutide Injectable Product, Calorie-restricted diet AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor NCT06699056n/a8 sites📍 Orange📍 Pasadena📍 Detroit Peerbridge Health, Inc · Tests: 15-minutes of sitting during COR ECG Acquistion Biomarkers for Left Ventricular Reverse Remodeling in Heart Failure (REVERT-HF) NCT07701876n/a1 site📍 Shanghai Ruijin Hospital Luwan Branch A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists NCT06033950Phase 3176 sites📍 Fairhope📍 Phoenix📍 Yuma Colorado Prevention Center · Tests: Finerenone, Placebo Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol in Heart Failure With Reduced Ejection Fraction Patients With Low vs. High Polygenic Score NCT07490067Phase 41 site📍 Ann Arbor University of Michigan · Tests: Metoprolol Succinate, Beta-Blocker Polygenic Score, Illumina Infinium Global Diversity Array with Enhanced Pharmacogeno… Dietary Intervention and Physical Activity in Patients With Heart Failure and Reduced Ejection Fraction NCT07595809NA1 site📍 Zabrze Medical University of Silesia · Tests: Resistance Exercise, Dietary Intervention Improving CRT Outcome With Non-Invasive Cardiac Mapping NCT05564793NA11 sites📍 Amsterdam📍 Groningen📍 Leiden EP Solutions SA · Tests: Pre-implantation planning, Post-implantation assessment A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction NCT07465653Phase 16 sites📍 Bradenton📍 Inverness📍 Jacksonville Novartis Pharmaceuticals · Tests: HJB647 low dose, HJB647 high dose, Placebo Demographic, Clinical, Biological, Treatment Characteristics and Cardiovascular Events of Patients With Heart Failure in Vietnam: a Multicenter Prospective Observational Study NCT06516562n/a1 site📍 Ho Chi Minh City University Medical Center Ho Chi Minh City (UMC) · Tests: Optimal treatment A Research Study Comparing CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Reduced/Mildly Reduced Ejection Fraction and Left Ventricular Hypertrophy NCT06979375Phase 292 sites📍 Concord📍 Brisbane📍 Adelaide Novo Nordisk A/S · Tests: CDR132L, Placebo Eccentric Muscle Training in Cardiac Rehabilitation NCT07636343NA1 site📍 Edegem University Hospital, Antwerp · Tests: eccentric bike training, eccentric overload training, aerobic treadmill training, aerobic bike training, traditional dy… A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF) NCT06991257Phase 2150 sites📍 Beverly Hills📍 Lake Forest📍 Santa Maria Pfizer · Tests: Placebo, Low Dose PF-07328948, Medium Dose PF-07328948, High Dose PF-07328948 Respiratory Sinus Arrhythmia Pacing Post-CABG Surgery in Patients With HFrEF NCT06384963NA3 sites📍 Adelaide📍 Melbourne📍 Hamilton Ceryx Medical Australia · Tests: Atrial pacing with respiratory sinus arrhythmia (RSA) variability, Monotonic right atrial overdrive pacing Comparison of Three-dimensional and Two-dimensional Left Ventricle Strain With Speckle-tracking Echocardiography in Heart Failure With Reduced and Mildly Reduced Ejection Fraction NCT07741305n/a5 sites📍 Bari📍 Milan📍 Pavia Istituti Clinici Scientifici Maugeri SpA Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction NCT06736574Phase 3209 sites📍 Alexander City📍 Birmingham📍 Tucson Cytokinetics · Tests: Omecamtiv Mecarbil (OM), Placebo Treating Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: Ablation or Medication NCT07272902NA4 sites📍 Halifax📍 Hamilton📍 London Nova Scotia Health Authority · Tests: Catheter Ablation for Atrial Fibrillation, Rate Control Medications (beta-blockers, calcium channel blockers, digoxin) Comparing Three Types of Specialist Pacemakers to Improve Heart Function and Reduce Rhythm Problems in Heart Failure NCT07430553NA1 site📍 London Imperial College London · Tests: Biventricular pacing, Conduction system pacing, Left bundle optimised cardiac resynchronisation therapy Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance NCT07131631n/a6 sites📍 Minneapolis📍 Charlotte📍 Cincinnati Minneapolis Heart Institute Foundation · Tests: Cardiac MRI
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