๐ŸŒ EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

๐Ÿงช

Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

๐ŸŽฏ Match trials to me

30 recruiting trials

for KRAS G12C Mutation

JAB-21822 Combined With JAB-3312 Compared SOC in the First Line for Treatment of Advanced Non-small Cell Lung Cancer With KRAS p.G12C Mutation NCT06416410Phase 337 sites๐Ÿ“ Hefei๐Ÿ“ Beijing๐Ÿ“ Beijing Allist Pharmaceuticals, Inc. ยท Tests: JAB-21822, Tislelizumab, JAB-3312, Pemetrexed, Carboplatin Fulzerasib Sequential Sintilimab Plus Platinum-Doublet Neoadjuvant Therapy for Resectable KRAS G12C-Mutant NSCLC NCT07492342Phase 23 sites๐Ÿ“ Beijing๐Ÿ“ Guangzhou๐Ÿ“ Zhejiang Jianxing He ยท Tests: fulzerasib A Phase I Clinical Study of HRS-7058 in Patients With Advanced Malignant Tumour NCT06383871Phase 11 site๐Ÿ“ Tianjin Shandong Suncadia Medicine Co., Ltd. ยท Tests: HRS-7058 capsule/ HRS-7058 tablet Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation NCT07012031Phase 1, Phase 29 sites๐Ÿ“ Sacramento๐Ÿ“ Tampa๐Ÿ“ Tampa National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test, Magnetic Resonance Imaging Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7 NCT04613596Phase 2, Phase 3770 sites๐Ÿ“ Goodyear๐Ÿ“ Prescott Valley๐Ÿ“ Safford Mirati Therapeutics Inc. ยท Tests: Adagrasib, Adagrasib, Adagrasib, Adagrasib, Pembrolizumab BBO-11818 in Adult Subjects With KRAS Mutant Cancer NCT06917079Phase 117 sites๐Ÿ“ Los Angeles๐Ÿ“ Sacramento๐Ÿ“ San Diego TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) ยท Tests: BBO-11818, Pembrolizumab, Platinum chemotherapy (cisplatin or carboplatin), Pemetrexed, Cetuximab A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies NCT07415031Phase 2101 sites๐Ÿ“ Phoenix๐Ÿ“ Bellflower๐Ÿ“ Long Beach Mirati Therapeutics Inc. ยท Tests: Adagrasib, Pembrolizumab, Cetuximab, Pemetrexed, Docetaxel A Clinical Study of Calderasib (MK-1084) in People With Advanced Solid Tumors (MK-1084-014) NCT07209111Phase 272 sites๐Ÿ“ Baltimore๐Ÿ“ Grand Rapids๐Ÿ“ Las Vegas Merck Sharp & Dohme LLC ยท Tests: Calderasib, Cetuximab A Study of D3S-001 Monotherapy or Combination Therapy in Subjects With Advanced Solid Tumors With a KRAS p.G12C Mutation NCT05410145Phase 1, Phase 252 sites๐Ÿ“ Orange๐Ÿ“ Palo Alto๐Ÿ“ Denver D3 Bio (Wuxi) Co., Ltd ยท Tests: D3S-001, Pembrolizumab, Cisplatin, Carboplatin, Pemetrexed A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC) NCT04929223Phase 184 sites๐Ÿ“ Birmingham๐Ÿ“ Phoenix๐Ÿ“ Duarte Hoffmann-La Roche ยท Tests: Inavolisib, Bevacizumab, Cetuximab, Atezolizumab, Tiragolumab A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors NCT06983743Phase 19 sites๐Ÿ“ Santa Rosa๐Ÿ“ Aurora๐Ÿ“ Sarasota Erasca, Inc. ยท Tests: ERAS-0015, ERAS-0015 in combination Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation NCT05288205Phase 1, Phase 227 sites๐Ÿ“ Hefei๐Ÿ“ Beijing๐Ÿ“ Beijing Allist Pharmaceuticals, Inc. ยท Tests: JAB-21822, JAB-3312 IBI351 Plus Cetuximab ฮฒ in Untreated Advanced Non-small Cell Lung Cancer With KRAS G12C Mutation NCT07198841Phase 27 sites๐Ÿ“ Guangzhou๐Ÿ“ Beijing๐Ÿ“ Foshan Guangdong Association of Clinical Trials ยท Tests: IBI351 combined with cetuximab ฮฒ A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer (MK-3475-01F) NCT07286149Phase 1, Phase 229 sites๐Ÿ“ Clermont๐Ÿ“ Chicago๐Ÿ“ Portland Merck Sharp & Dohme LLC ยท Tests: MK-1084, Patritumab deruxtecan, Sacituzumab tirumotecan, Cetuximab, Rescue Medications An Open-label, Multicenter, Phase II Clinical Study to Evaluate HRS-7058 in Patients With Pancreatic Cancer NCT07589569Phase 22 sites๐Ÿ“ Nanjing๐Ÿ“ Tianjin Shandong Suncadia Medicine Co., Ltd. ยท Tests: HRS-7058 A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib as a Single Agent or in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation NCT05789082Phase 1, Phase 271 sites๐Ÿ“ Duarte๐Ÿ“ Huntington Beach๐Ÿ“ Irvine Hoffmann-La Roche ยท Tests: Divarasib, Pembrolizumab, Carboplatin, Cisplatin, Pemetrexed A Clinical Trial of Calderasib (MK-1084) and Durvalumab in People With Non-Small Cell Lung Cancer (MK-1084-015/KANDLELIT-015) NCT07554339Phase 3103 sites๐Ÿ“ Savannah๐Ÿ“ Lisle๐Ÿ“ Lincoln Merck Sharp & Dohme LLC ยท Tests: Calderasib, Durvalumab, Placebo to MK-1084 A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4) NCT06875310Phase 3317 sites๐Ÿ“ Birmingham๐Ÿ“ Springdale๐Ÿ“ Fullerton Mirati Therapeutics Inc. ยท Tests: Adagrasib, Pembrolizumab, Carboplatin, Pemetrexed, Placebo DHF-20-1839-2: Clinical Performance Study Protocol for Therascreenยฎ KRAS RGQ PCR Kit NCT06645236NA1 site๐Ÿ“ Manchester QIAGEN Gaithersburg, Inc ยท Tests: therascreenยฎ KRAS RGQ PCR Kit A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors NCT07094204Phase 122 sites๐Ÿ“ Santa Monica๐Ÿ“ Atlanta๐Ÿ“ Jefferson Astellas Pharma Inc ยท Tests: ASP5834, panitumumab A Study of Sotorasib in People With Non-Small Cell Lung Cancer NCT06582771Phase 27 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: Sotorasib A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer NCT06119581Phase 3416 sites๐Ÿ“ Huntsville๐Ÿ“ Gilbert๐Ÿ“ Phoenix Eli Lilly and Company ยท Tests: LY3537982, Pembrolizumab, Placebo, Cisplatin, Carboplatin A Phase II Study Evaluating JAB-21822 Monotherapy in Adult Patients With Pancreatic Cancer and Other Solid Tumors Harboring the KRAS p.G12C Mutation. NCT06008288Phase 231 sites๐Ÿ“ Hefei๐Ÿ“ Beijing๐Ÿ“ Beijing Allist Pharmaceuticals, Inc. ยท Tests: JAB-21822 A Phase 3 Study of IN10018 in Combination With D-1553 Versus Standard Therapy for First Line Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation NCT07174908Phase 311 sites๐Ÿ“ Beijing๐Ÿ“ Guangzhou๐Ÿ“ Zhengzhou InxMed (Shanghai) Co., Ltd. ยท Tests: IN10018 in combination with D-1553, anti-PD-1 monoclonal antibody in combination with platinum and pemetrexed A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007) NCT07190248Phase 3221 sites๐Ÿ“ Birmingham๐Ÿ“ Farmington๐Ÿ“ Stamford Merck Sharp & Dohme LLC ยท Tests: Calderasib, Pembrolizumab (+) Berahyaluronidase alfa, Pemetrexed, Cisplatin, Carboplatin SKB264 Plus Glecirasib in Advanced KRAS G12C-Mutant NSCLC: A Phase II Study NCT07670013Phase 21 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: SKB264, Goleirex A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012) NCT06997497Phase 3244 sites๐Ÿ“ Phoenix๐Ÿ“ Fountain Valley๐Ÿ“ Los Angeles Merck Sharp & Dohme LLC ยท Tests: Calderasib, Oxaliplatin, Leucovorin/levofolinate calcium, 5-Fluorouracil, Cetuximab Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung Cancer NCT06249282Phase 12 sites๐Ÿ“ Duarte๐Ÿ“ Irvine City of Hope Medical Center ยท Tests: Biopsy, Biospecimen Collection, Carfilzomib, Computed Tomography, Echocardiography MK-3475AยฑCalderasib (MK-1084) in Completely Resected Stage IIA-IIIB (N2) KRAS G12Cm NSCLC (MK-1084-013) NCT07431827Phase 3117 sites๐Ÿ“ Ciudad Autรณnoma de Buenos Aires๐Ÿ“ Rosario๐Ÿ“ CABA Merck Sharp & Dohme LLC ยท Tests: Calderasib, MK-3475A, Placebo JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration NCT06973564Phase 1, Phase 24 sites๐Ÿ“ Rochester๐Ÿ“ St Louis๐Ÿ“ Cleveland Jacobio Pharmaceuticals Co., Ltd. ยท Tests: JAB-23E73, Cetuximab
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy