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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Low Rectal Cancer

The Ohio State University (OSU) SCREEN Community Program NCT06666192NA1 site📍 Columbus Ohio State University Comprehensive Cancer Center · Tests: Cancer Screening, Discussion, Educational Activity, Educational Intervention, Focus Group Screening for Anal Cancer in Men Who Have Sex With Men Using Pre-Exposure Prophylaxis NCT07029152NA8 sites📍 Bruges📍 Brussels📍 Brussels Universitair Ziekenhuis Brussel · Tests: Anal smear, Self-administered questionnaire, EQ-5D-5L questionnaire, High Resolution Anoscopy (HRA) Low Stable Pressure Pneumoperitoneum in Colorectal Surgery (CROSS STUDY) NCT06154785n/a18 sites📍 Jette📍 Besançon📍 Bordeaux Bordeaux Colorectal Institute Academy A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02) NCT06330064Phase 1, Phase 2120 sites📍 Los Angeles📍 Los Angeles📍 Whittier Daiichi Sankyo · Tests: Ifinatamab deruxtecan Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal Cancer NCT05943444NA1 site📍 Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University · Tests: Parks technique, Bacon technique Low Versus Standard Intraabdominal Pressure in Robot-assisted Colorectal Cancer Surgery NCT06783244NA1 site📍 Copenhagen NV Victoria Rosberg · Tests: Low intraabdominal pressure (8 mmHg) To Explore the Efficacy of Sintilimab Combined With Bevacizumab in Rectal Cancer NCT06808412Phase 21 site📍 Xi'an xiaohua li · Tests: sintilimab combined with bevacizumab and XELOX Tumor Local Excision +Postoperative Adjuvant Chemoradiotherapy for T1-2N0M0 Low/Ultra-Low Rectal Cancer NCT06949098Phase 21 site📍 Shijiazhuang Hebei Medical University Fourth Hospital · Tests: Local Tumor Resection, Radiotherapy, Chemotherapy Modified Long-Course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for MSS/pMMR High-risk Mid/Low LARC (MODIFI-RC-I) NCT06923345Phase 21 site📍 Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University · Tests: Reduced CTV, Conventional CTV PRE-ISPY Phase I/II Oncology Platform Program NCT05868226Phase 1, Phase 210 sites📍 Birmingham📍 Phoenix📍 Aurora QuantumLeap Healthcare Collaborative · Tests: ALX148, Fam-Trastuzumab Deruxtecan-Nxki, Zanidatamab, Tucatinib, TTX-MC138 Neoadjuvant Chemoradiotherapy Combined With QL1706 for MSS-Type Low-Rectal Cancer NCT07866313Phase 2, Phase 31 site📍 Shanghai Changhai Hospital · Tests: Neoadjuvant short-term radiotherapy and chemotherapy + iparomlimab and tuvonralimab, Neoadjuvant long-term radiotherapy… EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors NCT07410676Phase 1, Phase 21 site📍 Beijing Essen Biotech · Tests: EBNK-001 + IL-15 + Pembrolizumab The Efficacy and Safety of Short-course Radiation Combined With Adebrelimab and CAPEOX Neo-adjuvant Therapy for Organ-retention in Patients With MSS/pMMR Ultra Low Rectal Adenocarcinoma NCT06266832Phase 21 site📍 Hangzhou Sir Run Run Shaw Hospital · Tests: Adebrelimab, Oxaliplatin, Capecitabine, Short-course Radiation, Biopsy Zanzalintinib Alone or in Combination With Pembrolizumab and Berahyaluronidase Alfa in Participants With Colorectal Cancer With Molecular Residual Disease NCT07750158Phase 313 sites📍 Council Bluffs📍 Grand Island📍 Grand Island Exelixis · Tests: Zanzalintinib, Pembrolizumab (+) Berahyaluronidase alfa, Placebo Low and Intermediate Risk OliGometastatic ColoREctal CancEr PatieNts Treated with Stereotactic ABlative Radiotherapy NCT06310564NA1 site📍 Negrar IRCCS Sacro Cuore Don Calabria di Negrar · Tests: SABR Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance NCT06936774Phase 35 sites📍 Basel📍 Bern📍 Bern University Hospital, Basel, Switzerland · Tests: Intensified follow-up program Postoperative Effects of Different Enterostomy Approaches NCT05853094NA1 site📍 Shanghai Fudan University · Tests: Ileostomy, Transverse colostomy Neoadjuvant Long-course Chemoradiation Plus PD-1 Blockade for Mid-low Locally Advanced Rectal Cancer NCT05245474Phase 28 sites📍 Beijing📍 Beijing📍 Beijing Beijing Friendship Hospital · Tests: Long-course chemoradiation, with or without Tislelizumab (PD-1 inhibitor) MRD-guided Deferred Adjuvant Therapy in Resectable Early-stage Colon Cancer NCT06204484NA1 site📍 Guangzhou Sun Yat-sen University · Tests: CAPEOX adjuvant therapy, deferred CAPEOX adjuvant therapy, mFOLFOXIRI intensive adjuvant therapy Nodes-sparing Short-course Radiation Combined With CAPOX and Tislelizumab for MSS Middle and Low Rectal Cancer NCT05972655Phase 21 site📍 Hanzhou Sir Run Run Shaw Hospital · Tests: Modified short-course radiotherapy, PD-1 antibody, Capecitabine, Oxaliplatin Choice of the Optimal Treatment Strategies for Mid-low REctal Cancer NCT05871762n/a1 site📍 Beijing Peking Union Medical College Hospital · Tests: Registry study, no specific intervention Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer. NCT06758830Phase 2, Phase 31 site📍 Vilnius National Cancer Center Affiliate of Vilnius University Hosp… · Tests: Radiation Therapy, Chemoradiotherapy, Consolidation Chemotherapy, Surgery, Part two Study of Brain-Gut Function Reconstruction After Intersphincteric Resection for Ultra-Low Rectal Tumors NCT06082648NA1 site📍 Shanghai Huashan Hospital · Tests: Transcranial magnetic stimulation, Sham Transcranial magnetic stimulationt Node-Sparing Short-Course Radiation Combined With Capecitabine and PD-1/CTLA-4 for MSS Early Rectal Cancer NCT07068763Phase 21 site📍 Hangzhou Sir Run Run Shaw Hospital · Tests: Lymph-node-sparing short-course radiotherapy, Capecitabine, PD-1/CTLA-4 inhibitor (Aiparolitoworixureli injection) A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer NCT07321106Phase 110 sites📍 Phoenix📍 Duarte📍 Los Angeles Cartography Biosciences · Tests: CBI-1214 Antegrade Intestinal Fluid Reinfusion for Prevention of Low Anterior Resection Syndrome After Low Anterior Resection: a Single-Center, Prospective Randomized Controlled Trial. NCT07537998Phase 2, Phase 31 site📍 Guangzhou Pei-Rong Ding · Tests: intestinal fluid infusion, potable water Study on the Efficacy and Safety of Neoadjuvant Radiotherapy Combined With Tislelizumab, Liposomal Irinotecan, and Capecitabine in the Treatment of pMMR Locally Advanced Rectal Adenocarcinoma With Low Rectal Involvement NCT07104604Phase 22 sites📍 Shantou📍 Shantou Affiliated Cancer Hospital of Shantou University Medical Co… · Tests: Liposomal Irinotecan+Tislelizumab+Capecitabine+Rradiotherapy A Single-center, Phase II Study on Efficacy & Safety of SCRT+CAPOX+Serplulimab+Bevacizumab for MSS Rectal Cancer NCT07347951Phase 21 site📍 Wenzhou First Affiliated Hospital of Wenzhou Medical University · Tests: Short-course radiotherapy, CAPOX chemotherapy, Targeted therapy with bevacizumab, Serplulimab immunotherapy Neoadjuvant Chemoradiotherapy Plus Tislelizumab With or Without Probio-M9 in pMMR/MSS Locally Advanced Rectal Cancer NCT07458529Phase 21 site📍 Beijing Seventh Medical Center of PLA General Hospital · Tests: CRT+PD-1 inhibitor+Probio-M9, CRT+PD-1 inhibitor+placebo The Safety and Efficacy of Transanal Irrigation in Patients With Sleep Disturbance From Low Anterior Resection Syndrome After Rectal Cancer Surgery (TraLARS) NCT06222255NA1 site📍 Seoul Seoul National University Hospital · Tests: Transanal Irrigation (TAI)
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