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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Lupus Nephritis

Safety and Efficacy of PRG-1801 for Refractory Lupus Nephritis and IgG4-Related Disease NCT06497387EARLY Phase 11 site๐Ÿ“ Wuhan Tongji Hospital ยท Tests: PRG-1801 A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants NCT05039619Phase 244 sites๐Ÿ“ Loma Linda๐Ÿ“ San Francisco๐Ÿ“ Aurora Hoffmann-La Roche ยท Tests: Obinutuzumab, Placebo, Mycophenolate Mofetil, Acetaminophen/paracetamol, Diphenhydramine hydrochloride (HCl) Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID) NCT01802034n/a1 site๐Ÿ“ New York The Rogosin Institute Induction Therapy for Lupus Nephritis With no Added Oral Steroids: A Trial Comparing Oral Corticosteroids Plus Mycophenolate Mofetil (MMF) Versus Obinutuzumab and MMF NCT04702256Phase 31 site๐Ÿ“ Paris Assistance Publique - Hรดpitaux de Paris ยท Tests: Obinutuzumab administration, Administration of Methylprednisolone + Prednisone + Mycophenolate mofetil, Administration โ€ฆ KOrea Renal Biobank NEtwoRk System TOward NExt-generation Analysis NCT03929887n/a6 sites๐Ÿ“ Chuncheon๐Ÿ“ Daegu๐Ÿ“ Seoul Seoul National University Hospital ยท Tests: Kidney Biopsy A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1) NCT06557265Phase 1, Phase 219 sites๐Ÿ“ Little Rock๐Ÿ“ Tustin๐Ÿ“ Gainesville Nkarta, Inc. ยท Tests: NKX019, Fludarabine, Cyclophosphamide To Evaluate the Effects of Cevostamab in Participants With Systemic Lupus Erythematosus With or Without Active Lupus Nephritis NCT07629583Phase 12 sites๐Ÿ“ Toulouse๐Ÿ“ Seville Genentech, Inc. ยท Tests: Cevostamab, Tocilizumab Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Systemic Lupus Erythematosus NCT06585514Phase 1, Phase 21 site๐Ÿ“ Beijing Beijing GoBroad Hospital ยท Tests: CD19 CAR-T cells Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders NCT06434363Phase 1, Phase 22 sites๐Ÿ“ Houston๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Tafasitamab, Fludarabine phosphate, Cyclophosphamide, Tafasitamab and NK cells A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease NCT07085104Phase 117 sites๐Ÿ“ Phoenix๐Ÿ“ Loma Linda๐Ÿ“ Aurora Allogene Therapeutics ยท Tests: ALLO-329, Cyclophosphamide, Fludarabine Correlation Between Serum Uric Acid, Serum Homocysteine Level and Interleukin- 17 in Lupus Nephritis Patients NCT07017868n/a1 site๐Ÿ“ Sohag Sohag University ยท Tests: interleukin- 17 SGLT2 Inhibitor in Lupus Nephritis Patients With Chronic Kidney Disease NCT06155604Phase 21 site๐Ÿ“ Hong Kong The University of Hong Kong ยท Tests: Dapagliflozin 10mg Tab, Standard maintenance therapy The Efficacy of Empagliflozin on Kidney Functions in Lupus Nephritis Population NCT07700940Phase 41 site๐Ÿ“ Banฤซ Suwayf Ahmed Yehia Ismail ยท Tests: Empagliflozin (25 Mg Tab) along with standard medical therapy, Placebo and standard of care A Clinical Study of YTS109 Cell for R/R Autoimmune Diseases NCT07104721Phase 11 site๐Ÿ“ Hefei China Immunotech (Beijing) Biotechnology Co., Ltd. ยท Tests: YTS109 cell High Quality Evidence of Guangzhou Lupus Nephritis Cohort (HOPE Cohort) NCT06682507n/a1 site๐Ÿ“ Guangzhou First Affiliated Hospital, Sun Yat-Sen University ยท Tests: No Intervention: Observational Cohort Exploring Biomarkers for Therapeutic Response of Lupus Nephritis Based on Multi Omics Analysis NCT06167174n/a1 site๐Ÿ“ Beijing Chinese SLE Treatment And Research Group Pakistan Arthritis and Connective Tissue Disease Network - Systemic Lupus Erythematosus NCT07902622n/a1 site๐Ÿ“ Rawalpindi Foundation University Islamabad ยท Tests: no active ingredient Per-protocol Repeat Kidney Biopsy in Incident Cases of Lupus Nephritis NCT04449991NA1 site๐Ÿ“ Stockholm Karolinska Institutet ยท Tests: Repeat kidney biopsy Treatment of Lupus Nephritis With Allogeneic Mesenchymal Stem Cells NCT03673748Phase 21 site๐Ÿ“ Valladolid Red de Terapia Celular ยท Tests: Mesenchymal stem cells (MSC), Placebo Safety and Efficacy of Combination Belimumab and Voclosporin in the Treatment of Proliferative Forms of Lupus Glomerulopathy: Synergy Trial NCT07225387Phase 47 sites๐Ÿ“ Glendale๐Ÿ“ Atlanta๐Ÿ“ Lawrenceville NephroNet, Inc. ยท Tests: Voclosporin Safety and Efficacy of PRG-2311 for Refractory Lupus Nephritis and IgG4-Related Disease NCT06497361EARLY Phase 11 site๐Ÿ“ Wuhan Tongji Hospital ยท Tests: PRG-2311 Study of Systemic Lupus Erythematosus NCT00001372n/a1 site๐Ÿ“ Bethesda National Institute of Arthritis and Musculoskeletal and Skiโ€ฆ Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor NCT05508009Phase 1, Phase 21 site๐Ÿ“ Palo Alto Alice Bertaina ยท Tests: Cyclophosphamide 1200 mg/Kg, Fludarabine, Cyclophosphamide 100 mg/Kg, Total Body Irradiation, ATG A Phase 1 Study of HB2198 in Participants With Moderately to Severely Active Systemic Lupus Erythematosus (SLE) NCT07491900Phase 11 site๐Ÿ“ Brisbane Hinge Bio ยท Tests: HB2198 UB-VV410 in Subjects With Active Refractory Systemic Lupus Erythematosus or Lupus Nephritis NCT07109986Phase 11 site๐Ÿ“ Nanjing Nanjing IASO Biotechnology Co., Ltd. ยท Tests: UB-VV410 Chimeric Antigen Receptors T Cells for Refractory/Recurrent Lupus Nephritis in Children NCT06904729Phase 31 site๐Ÿ“ Guangzhou Guangzhou Women and Children's Medical Center ยท Tests: Low-dose CAR-T cells group, High-dose CAR-T cells group A Study to Evaluate Mosunetuzumab in Participants With Systemic Lupus Erythematosus With or Without Active Lupus Nephritis NCT07598396Phase 224 sites๐Ÿ“ CABA๐Ÿ“ Buenos Aires๐Ÿ“ Salvador Hoffmann-La Roche ยท Tests: Mosunetuzumab Dose Escalation Study With Bispecific Antibodies in Adult Participants With Lupus Nephritis NCT06975787Phase 120 sites๐Ÿ“ San Francisco๐Ÿ“ Gainesville๐Ÿ“ Rochester Regeneron Pharmaceuticals ยท Tests: Vonsetamig, Odronextamab CD19-BCMA CART Cell Therapy for Refractory SLE-LN, SSc, and pSS-PAH NCT06947460Phase 1, Phase 21 site๐Ÿ“ Beijing Beijing GoBroad Hospital ยท Tests: CD19-BCMA CAR-T cells infusion Dapagliflozin in Active Lupus Nephritis NCT07323524Phase 42 sites๐Ÿ“ Boston๐Ÿ“ Boston Brigham and Women's Hospital ยท Tests: Dapagliflozin (10Mg Tab) along with standard medical therapy, Placebo
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