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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Malignant Digestive System Neoplasm

Study of CEA Targeting CAR-T (PTC13) in the Treatment of CEA-Positive Advanced Malignant Solid Tumors NCT06821048Phase 11 site📍 Hangzhou Weijia Fang, MD · Tests: Intraperitoneal infusion of FAST CEA-targeted CAR-T An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors NCT07371663Phase 1, Phase 23 sites📍 Beijing📍 Zhengzhou📍 Hangzhou Beijing Tide Pharmaceutical Co., Ltd · Tests: TCC1727 tablet 90mg, TCC1727 tablet 120mg, TCC1727 tablet 160mg, benmelstobart Injection Low Stable Pressure Pneumoperitoneum in Colorectal Surgery (CROSS STUDY) NCT06154785n/a18 sites📍 Jette📍 Besançon📍 Bordeaux Bordeaux Colorectal Institute Academy Application of ICG@HSA Complexes in Fluorescence Image-Guided Laparoscopic Anatomical Liver Resection NCT06219096NA1 site📍 Chengdu West China Hospital · Tests: NIF image-guided laparoscopic anatomical liver resection with the novel ICG@HSA administration, NIF image-guided laparo… Precision Navigation to Improve Community Cancer Screening Participation NCT07676383NA3 sites📍 Huaihua📍 Shaoyang📍 Yongzhou Hunan Cancer Hospital · Tests: Precision Navigation Intervention, Usual Health Education Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity NCT04273061Phase 22 sites📍 Vancouver📍 Toronto British Columbia Cancer Agency · Tests: Atezolizumab Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers NCT04221893NA2 sites📍 San Francisco📍 Walnut Creek University of California, San Francisco · Tests: Radiation Therapy (RT) Vasodilator Therapy With Isosorbide Mononitrate or Diltiazem to Reduce Vasotoxicity in Patients With Gastrointestinal Cancer Receiving Fluoropyrimidine Therapy NCT07456852Phase 1, Phase 21 site📍 Rochester Mayo Clinic · Tests: Biospecimen Collection, Capecitabine, Diltiazem Hydrochloride, Electrocardiogram, Fluorouracil A Study of BMS-986488 as Monotherapy and Combination Therapy in Participants With Advanced Malignant Tumors NCT06764771Phase 18 sites📍 Hackensack📍 Allentown📍 Germantown Bristol-Myers Squibb · Tests: BMS-986488, Adagrasib, Cetuximab, Nivolumab Effect of Geriatric Intervention in Frail Patients with Gastric, Biliary, and Pancreatic Cancer Receiving Palliative Chemotherapy NCT06040801NA1 site📍 Taoyuan Chang Gung Memorial Hospital · Tests: Frailty intervention measures DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition NCT05770102Phase 2, Phase 327 sites📍 Belfast📍 Birmingham📍 Birmingham Cancer Research UK · Tests: Atezolizumab Adaptive Radiation for Abdominopelvic Metastases NCT05880667Phase 11 site📍 Philadelphia Fox Chase Cancer Center · Tests: Adaptive Stereotactic Body Radiation A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy NCT06362369Phase 1, Phase 25 sites📍 Aurora📍 Lake Mary📍 Lebanon 7 Hills Pharma, LLC · Tests: Alintegimod, Ipilimumab, Nivolumab A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors NCT06043466Phase 12 sites📍 Hangzhou📍 Hangzhou Chongqing Precision Biotech Co., Ltd · Tests: CEA-targeted CAR-T cells Establishment of a Biological Collection to Develop Translational Preclinical Models for the Study of Tumors and Diseases of the Gastrointestinal Tract NCT07782203NA1 site📍 Strasbourg University Hospital, Strasbourg, France · Tests: biopsy A Clinical Study of GK02 in Malignant Ascites NCT07378436EARLY Phase 11 site📍 Beijing Beijing Geekgene Technology Co., LTD · Tests: GK02 BOLSTER: Learning New Skills to Thrive NCT06936878NA2 sites📍 Boston📍 Houston Dana-Farber Cancer Institute · Tests: BOLSTER Program A Study of NX-1607 in Adults With Advanced Malignancies NCT05107674Phase 117 sites📍 Duarte📍 Los Angeles📍 San Francisco Nurix Therapeutics, Inc. · Tests: NX-1607, Paclitaxel A Phase I, First in Human Study of CBA-1205, Anti-DLK1 Monoclonal Antibody in Patients With Advanced Solid Tumors, Hepatocellular Carcinoma (HCC), Melanoma, and Pediatric Cancer NCT06636435Phase 15 sites📍 Kashiwa📍 Yokohama📍 Niigata Chiome Bioscience Inc. · Tests: CBA-1205 Part 1, CBA-1205 Part 2, CBA-1205 Part 3, CBA-1205 Part 4, CBA-1205 Part 5 Treatment Recommendations for Gastrointestinal Cancers Via Large Language Models NCT06002425NA7 sites📍 Duarte📍 Jiangmen📍 Zhuhai Chinese Academy of Sciences · Tests: Clinician-Directed Treatment Plan, ChatGPT-Assisted Treatment Plan Novel Humanized Ferritin-Based NIR Fluorescent Probe for Identifying Sentinel Lymph Node Metastasis in Early Gastric Cancer NCT07294638n/a1 site📍 Guangzhou Nanfang Hospital, Southern Medical University · Tests: VE/CX-FTn-ICG injection solution Genetics of Appendix Cancer Study NCT05734430n/a1 site📍 Nashville Andreana Holowatyj, PhD, MSCI · Tests: Genetic profiling, Retrospective tissue procurement Non-inferiority Study Comparing Salvage Pelvic Radiotherapy in 25 Fractions (62.5 Gy/25) Versus 20 Fractions (52.5 Gy/20) for Recurrent Prostate Cancer After Surgery. NCT07483658NA4 sites📍 Gatineau📍 Montreal📍 Montreal CHU de Quebec-Universite Laval · Tests: Standard Fractionation Post-Operative Salvage Radiotherapy (25 fractions), Hypofractionated Post-Operative Salvage Radi… EUS Guided HVA and PVA for Circulating Tumor DNA in Patients NCT04782557NA1 site📍 Hong Kong Chinese University of Hong Kong · Tests: EUS-guided portal vein and hepatic vein aspiration Molecular Basis of Pediatric Liver Cancer NCT03959800n/a1 site📍 Pittsburgh University of Pittsburgh Efficacy of Neoadjuvant Chemotherapy in Terms of DFS in Patients With Localized Digestive Neuroendocrine Carcinomas NCT04268121Phase 214 sites📍 Amiens📍 Besançon📍 Clichy GERCOR - Multidisciplinary Oncology Cooperative Group · Tests: Neoadjuvant treatment, Adjuvant treatment A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors NCT07070232Phase 1, Phase 277 sites📍 Phoenix📍 San Francisco📍 Hartford BioNTech SE · Tests: BNT326, Pumitamig, Itraconazole, Paroxetine Delayed Systemic Therapy Following Destructive Local Treatment of Pulmonary Oligometastases After No Evidence of Disease (NED) in Colorectal Cancer. NCT06778382Phase 21 site📍 Jinan Shandong Cancer Hospital and Institute · Tests: Oligometastasis Treatment GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors NCT06265025Phase 1, Phase 24 sites📍 Goyang-si📍 Seoul📍 Seoul GeneMedicine Co., Ltd. · Tests: GM103 (Part A), GM103 (Part B), GM103 and Pembrolizumab (Part C) A Study Evaluating the Safety and Efficacy of AUR107 in Patients With Relapsed Advanced Malignancies (SHAKTI-1) NCT05865002Phase 137 sites📍 Vijayawada📍 Visakhapatnam📍 Chandigarh Aurigene Discovery Technologies Limited · Tests: AUR107
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