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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Primary Progressive Aphasia(PPA)

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a1 site📍 Sioux Falls Sanford Health The Skin as a Window to the Central Nervous System in Frontotempolar Lombar Degeneration NCT06490822NA1 site📍 Nantes Nantes University Hospital · Tests: Skin biopsy Stimulating the Aging Brain Using Brain and Sensory Stimulation NCT07650188NA1 site📍 Milwaukee Medical College of Wisconsin · Tests: tACS or multisensory stimulation Educational Support Group Program for Bilingual and Spanish-speaking Carepartners and People With Progressive Aphasia NCT06511752EARLY Phase 11 site📍 Austin University of Texas at Austin · Tests: Psychosocial educational, support group and implementation of strategies Retinal Imaging in Neurodegenerative Disease NCT03233646n/a1 site📍 Durham Duke University · Tests: Retinal and Choroidal Imaging Automated Language Analysis in Neurodegenerative Diseases: Application of Artificial Intelligence Models NCT07906769NA1 site📍 Bari Istituti Clinici Scientifici Maugeri SpA · Tests: Speech and language Test to support clinical diagnosis Links Between Self-awareness and Sociocognitive Processes in Neurodegenerative Diseases NCT07531732n/a1 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: Computer-based facial expression recognition task, Computerized affective task, UCLA Structured Insight Interview, Barb… A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis NCT07054515Phase 339 sites📍 Oakland📍 Minneapolis📍 Rochester Azafaros B.V. · Tests: AZ-3102, Placebo Proteinopathies Expression in Skin of Neurodegenerative Disorders NCT06528964n/a1 site📍 San Luis Potosí City Universidad Autonoma de San Luis Potosí · Tests: Immunohistochemistry and immunofluorescence Molecular Neuroimaging of Neuroinflammation in Neurodegenerative Dementias NCT02945774NA1 site📍 London London Health Sciences Centre Research Institute OR Lawson … · Tests: (18F)-FEPPA Effects of Transcranial Direct Current Stimulation (tDCS) on Inhibition and Brain Function in Primary Progressive Aphasia NCT06473714NA1 site📍 Nice Centre Hospitalier Universitaire de Nice · Tests: tDCS, SHAM STELLA-FTD: Examination of a Behavior Change Intervention for FTD Family Care Partners NCT06613204NA1 site📍 Portland Oregon Health and Science University · Tests: STELLA-FTD Control, STELLA-FTD Test Diagnosing Frontotemporal Lobar Degeneration NCT02964637n/a1 site📍 Toronto University Health Network, Toronto · Tests: Observational Study Amyotrophic Lateral Sclerosis (ALS) Families Project NCT03865420n/a1 site📍 New York Columbia University Memory and Social Interactions NCT05800028n/a1 site📍 Caen University Hospital, Caen · Tests: Learning new information Daridorexant for Alzheimer Disease Prevention NCT07213349Phase 21 site📍 Montreal Douglas Mental Health University Institute · Tests: Daridorexant 50 mg, Placebo Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling NCT06529744n/a4 sites📍 North York📍 Toronto📍 Toronto University Health Network, Toronto Long Term Effect of Brain Stimulation in PPA NCT07158216NA1 site📍 Madrid Hospital San Carlos, Madrid · Tests: TMS, tDCS, Sham TMS, Sham tDCS A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC) NCT07082725Phase 334 sites📍 Oakland📍 Minneapolis📍 Rochester Azafaros B.V. · Tests: Nizubaglustat, Placebo The Pre-symptomatic Familial Amyotrophic Lateral Sclerosis (Pre-fALS) Study NCT00317616n/a1 site📍 Miami University of Miami Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech NCT01818661Phase 41 site📍 Rochester Mayo Clinic · Tests: AV-1451 Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia NCT05386394Phase 23 sites📍 Baltimore📍 Philadelphia📍 Toronto Johns Hopkins University · Tests: Active tDCS + Language Therapy, Sham tDCS + Language Therapy Incremental Diagnostic Value of Tau-PET With [18F]RO948 vs Amyloid-PET in Patients With Cognitive Impairment NCT06618872NA2 sites📍 Geneva📍 Lausanne University Hospital, Geneva · Tests: PET/CT with RO958 (experimental) Propranolol in Primary Progressive Aphasia NCT06066710EARLY Phase 11 site📍 Columbia University of Missouri-Columbia · Tests: Propranolol, Magnetic Resonance Imaging (MRI), Placebo First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia NCT05374278Phase 1, Phase 21 site📍 San Francisco David Wilson · Tests: [18F]RP-115 PET/MRI or PET/CT and MRI Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia NCT03225144n/a1 site📍 Bethesda National Institute of Neurological Disorders and Stroke (NI… The Neurobiology of Two Distinct Types of Progressive Apraxia of Speech NCT03313011n/a1 site📍 Rochester Mayo Clinic · Tests: Testing protocol for the study A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease NCT06297590Phase 110 sites📍 Maitland📍 The Villages📍 Decatur Eli Lilly and Company · Tests: LY3954068, Placebo, Flortaucipir F18 Speech and Language Interventions for Italian People With PPA NCT06739967n/a2 sites📍 Bari📍 Milan Istituti Clinici Scientifici Maugeri SpA · Tests: Behavioral Treatment Cerebro Spinal Fluid Collection (CSF) NCT04844060n/a1 site📍 Strasbourg University Hospital, Strasbourg, France · Tests: Lumbar punction
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