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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Hepatic Malignancies

Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease NCT06607458Phase 220 sites๐Ÿ“ Duarte๐Ÿ“ Santa Monica๐Ÿ“ Miami Delcath Systems Inc. ยท Tests: Melphalan/HDS Followed by Consolidation Treatment with Trifluridine-tipiracil plus Bevacizumab, Trifluridine-tipiracil โ€ฆ Can Hepatic-splenic Elastography Predict the Risk of Hepatocellular Recurrence After Radiofrequency Ablation? NCT06777017n/a1 site๐Ÿ“ Bologna IRCCS Azienda Ospedaliero-Universitaria di Bologna QL1706 in Combination With Bevacizumab and RALOX HAIC for Hepatocellular Carcinoma With Vp3/4 PVTT NCT07327788Phase 21 site๐Ÿ“ Guangzhou Nanfang Hospital, Southern Medical University ยท Tests: Iparomlimab and Tuvonralimab Injection (QL1706), Bevacizumab, Hepatic Arterial Infusion Chemotherapy with Raltitrexed aโ€ฆ A Study of Targeted Radiation Therapy in People With Non-Small Cell Lung Cancer (NSCLC) NCT05657873Phase 29 sites๐Ÿ“ Miami๐Ÿ“ Basking Ridge๐Ÿ“ Middletown Memorial Sloan Kettering Cancer Center ยท Tests: L-SABR, Anti-PD-(L)1 based immunotherapy, Platinum based chemotherapy Study to Evaluate the Pharmacokinetics and Safety of Pralatrexate in Patients With Advanced Solid Tumor or Hematological Malignancy and Either Normal Hepatic Function or Mild, Moderate, or Severe Hepatic Impairment NCT07036133Phase 14 sites๐Ÿ“ Cerritos๐Ÿ“ Chicago๐Ÿ“ Detroit Acrotech Biopharma Inc. ยท Tests: Pralatrexate Injection Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy NCT07201519Phase 21 site๐Ÿ“ Lexington Michael J Cavnar, MD ยท Tests: Hepatic Artery Infusion Pump (HAIP), Standard Treatment, Community Treatment, Systemic Chemotherapy Standard of Care, Sโ€ฆ Efficacy and Safety of Icaritin Combined With mFOLFOX in Postoperative HCC With High-risk Recurrence Factors NCT07337460Phase 21 site๐Ÿ“ Yangzhou Northern Jiangsu People's Hospital ยท Tests: Icaritin Soft Capsules and mFOLFOX ๏ผšOxaliplatin,leucovorin calcium,5-fluorouracil Cadonilimab in Combination With Lenvatinib and Hepatic Arterial Infusion Chemotherapy (HAIC) for the Treatment of Unresectable Hepatocellular Carcinoma NCT06406634Phase 21 site๐Ÿ“ Changsha Hunan Cancer Hospital ยท Tests: Cadonilimab, Lenvatinib Concurrently vs Sequentially Combined HAIC With Targeted and Immunotherapy in Potentially Resectable HCC NCT06041477Phase 31 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Oxaliplatin,calcium folinic acid, levofolinic acid, 5-FU, Concurrent Lenvatinib, Concurrent PD-1 antibody, Sequential Lโ€ฆ Atezolizumab and Bevacizumab Plus TACE-HAIC for Unresectable Advanced HCC: a Phase 2 Clinical Trial NCT05751343Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: TACE-HACI, plus atezolizumab-bevacizumab Effect of Laparoscopic Hepatectomy Combined With Splenectomy on Hepatic Functional Reserve and Immune Function NCT07811687n/a1 site๐Ÿ“ Yangzhou Northern Jiangsu People's Hospital Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Breast Cancer NCT06860815Phase 21 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Biopsy, Biospecimen Collection, Cemiplimab, Computed Tomography, Magnetic Resonance Imaging Radioembolization as a Spearhead Treatment of Hepatocellular Carcinoma With Localized Portal Vein Tumor Thrombosis NCT06166576Phase 25 sites๐Ÿ“ Ilsan๐Ÿ“ Seongnam-si๐Ÿ“ Seoul Seoul National University Hospital ยท Tests: Ablative radioembolization Hepatic Arterial Infusion Chemotherapy Plus Envafolimab and Lenvatinib for First-Line Unresectable Advanced Biliary Tract Cancer NCT07636798Phase 1, Phase 21 site๐Ÿ“ Chengdu West China Hospital ยท Tests: HAIC Combined Regimen Treatment Group An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer NCT06342414n/a5 sites๐Ÿ“ Duarte๐Ÿ“ Fukuoka๐Ÿ“ Kumamoto City of Hope Medical Center ยท Tests: ELUCIDATE Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment NCT04953910Phase 122 sites๐Ÿ“ Houston๐Ÿ“ Yerevan๐Ÿ“ Yerevan Taiho Oncology, Inc. ยท Tests: ASTX727 Phase 2 Combination of Melphalan/HDS Via PHP + Tebentafusp in Treating Metastatic Uveal Melanoma NCT07276386Phase 21 site๐Ÿ“ Tampa H. Lee Moffitt Cancer Center and Research Institute ยท Tests: Melphalan/HDS (Percutaneous Hepatic Perfusion), Tebentafusp Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis NCT07281924Phase 1, Phase 21 site๐Ÿ“ Madison University of Wisconsin, Madison ยท Tests: Nivolumab and Relatlimab, Melphalan Fluctuational Imaging for the Diagnosis of Hepatic Hemangioma: A Multicenter, Prospective Study NCT07418294n/a1 site๐Ÿ“ Seoul Yonsei University The DRAGON 2 Trial NCT05428735NA24 sites๐Ÿ“ New Haven๐Ÿ“ Clayton๐Ÿ“ Vienna Maastricht University ยท Tests: Embolization Preoperative Ketogenic Diet for Reduction of Hepatic Steatosis NCT05884723NA1 site๐Ÿ“ London Anton Skaro ยท Tests: Ketogenic Diet Endoscopic Variceal Ligation vs Carvedilol for the Prevention of First Esophageal Variceal Bleeding in Patients With HCC NCT06594744Phase 41 site๐Ÿ“ Taipei Taipei Veterans General Hospital, Taiwan ยท Tests: Endoscopic variceal ligation, Carvedilol EUS Guided HVA and PVA for Circulating Tumor DNA in Patients NCT04782557NA1 site๐Ÿ“ Hong Kong Chinese University of Hong Kong ยท Tests: EUS-guided portal vein and hepatic vein aspiration Clinical Study on the Safety, Efficacy, and Exploration of Immune Mechanisms of a Combined Multimodal Tumor Therapy System for Hepatic Malignancies NCT07459309NA1 site๐Ÿ“ Shanghai Fudan University ยท Tests: Multimodal Tumor Thermal Ablation Infusion of PD1/PDL1/CTLA4 Inhibitors Via Hepatic Arterial for Immunotherapy of Hepatocellular Carcinoma NCT03949231Phase 31 site๐Ÿ“ Guanzhou Second Affiliated Hospital of Guangzhou Medical University ยท Tests: PD1/PDL1 inhibitor Phase II Trial of Albumin-Bound Paclitaxel Combined With Nedaplatin (TP) Via Hepatic Arterial Infusion for Advanced Breast Cancer Patients With Liver Metastases After Failure of Standard Therapy NCT07284836Phase 21 site๐Ÿ“ Hangzhou Zhejiang Cancer Hospital ยท Tests: Abraxane, Nedaplatin Impact of Emotional Status on Prognosis of Patients With BCLC Stage B/C Hepatocellular Carcinoma Undergoing Hepatic Arterial Infusion Chemotherapy Combined With Targeted and Immunotherapy NCT07436845n/a1 site๐Ÿ“ Guangzhou Nanfang Hospital, Southern Medical University Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia NCT07359586n/a2 sites๐Ÿ“ Hangzhou๐Ÿ“ Hangzhou Zhejiang University Preoperative Oncogeriatric Assessment in Patients Undergoing Hepatectomy NCT07537569NA1 site๐Ÿ“ Roma Fondazione Policlinico Universitario Agostino Gemelli IRCCS ยท Tests: Comprehensive Geriatric Assessment (CGA) TACE Plus Atezolizumab/Bevacizumab and I-125 Seeds Brachytherapy for HCC With Branch PVTT NCT05984511NA1 site๐Ÿ“ Guangzhou Third Affiliated Hospital, Sun Yat-Sen University ยท Tests: I-125 Seeds Brachytherapy in PVTT, Transcatheter arterial chemoembolization, Atezolizumab plus Bevacizumab
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